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ALS - Amyotrophic lateral sclerosis | Miscellaneous | Heatlh & Medicine | Khan Academy

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Sal explains the disease ALS, amyotrophic lateral sclerosis, and takes the "ice bucket challenge.". Created by Sal Khan. Watch the next lesson: https://www.khanacademy.org/science/health-and-medicine/healthcare-misc/v/low-salt-diet?utm_source=YT&utm_medium=Desc&utm_campaign=healthandmedicine Missed the previous lesson? https://www.khanacademy.org/science/health-and-medicine/healthcare-misc/v/strokes?utm_source=YT&utm_medium=Desc&utm_campaign=healthandmedicine Health & Medicine on Khan Academy: No organ quite symbolizes love like the heart. One reason may be that your heart helps you live, by moving ~5 liters (1.3 gallons) of blood through almost 100,000 kilometers (62,000 miles) of blood vessels every single minute! It has to do this all day, everyday, without ever taking a vacation! Now that is true love. Learn about how the heart works, how blood flows through the heart, where the blood goes after it leaves the heart, and what your heart is doing when it makes the sound “Lub Dub.” About Khan Academy: Khan Academy is a nonprofit with a mission to provide a free, world-class education for anyone, anywhere. We believe learners of all ages should have unlimited access to free educational content they can master at their own pace. We use intelligent software, deep data analytics and intuitive user interfaces to help students and teachers around the world. Our resources cover preschool through early college education, including math, biology, chemistry, physics, economics, finance, history, grammar and more. We offer free personalized SAT test prep in partnership with the test developer, the College Board. Khan Academy has been translated into dozens of languages, and 100 million people use our platform worldwide every year. For more information, visit www.khanacademy.org, join us on Facebook or follow us on Twitter at @khanacademy. And remember, you can learn anything. For free. For everyone. Forever. #YouCanLearnAnything Subscribe to Khan Academy’s Health & Medicine channel: https://www.youtube.com/channel/UC1RAowgA3q8Gl7exSWJuDEw?sub_confirmation=1 Subscribe to Khan Academy: https://www.youtube.com/subscription_center?add_user=khanacademy
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Text Comments (145)
Dora Robison (17 days ago)
What is the "ice bucket challenge"??
Corrine Gaffin (2 months ago)
i was diagnosed 2011. i was diagnosed with the bulbar form of ALS and was given one year to live. My symptoms progressed quickly. Soon i was having difficulty breathing, swallowing and even walking short distances. With the help of Natural Herbal Garden natural herbs I have been able to reverse my symptoms using diet, herbs, which i feel has made the most difference. The ALS natural formula immensely helped my condition, it reversed my ALS. my slurred speech. And then the inability to eat without getting choked, breathing, and coughing. gradually disappeared. Visit NATURAL HERBAL GARDENS via their official web-site www. naturalherbalgardens. com. I’m now playing golf again. and i turned 69 today. i am glad to get my life back DON’T GIVE UP HOPE!!!
Hafizah Hoshni (2 months ago)
Amazing! I am so thankful for sharing your expertise and knowledge. Thank you so much! 11/8/2018
4VeganLife (5 months ago)
Look into spiders
Sir Darwin Dante (7 months ago)
RIP steve hawkings
Patricia Mendez (8 months ago)
And its a HORRIBLE. disease!!! And my brother is only 34! He got diagnosed when he was 30. He has 2 daughters that keep him fighting daily he wishes he could hold he wishes he can feed them run with them even talk to them. But ALS is doing its thing and we are losing my brother. But seeing him and other families go through this makes me not take for granted every movement that i can make on my own!
Patricia Mendez (8 months ago)
My brother has ALS and his is not genetic his is sporadic
Percy Carry (9 months ago)
Lou Gehrig is not the greatest baseball player of all time.
Piotr Czary (9 months ago)
it is about fascia not muscles.
Atheer (11 months ago)
How is that supposed to help me for my exam ? Well thanks anyway 🤔❤️
Rafael Figueroa (1 year ago)
There are a few components to treating ms at home. One resource I discovered which succeeds in merging these is the Denelle Multi Care (check it out on google) without a doubt the most useful resource that I have ever seen. Check out all the great info .
Muzzammil Sayyad (1 year ago)
learn something from osmosis
Jordan Weil (1 year ago)
Really great video, but I'd be worried about anyone studying from this material. The upper motor neuron drawing around 53 seconds is wrong. Upper motor neurons end when they synapse on the lower motor neuron in spinal cord (or thereabouts: anterior grey matter, cranial nerve nuclei, etc.). Upper motor neurons don't touch muscles. ALS degrades both upper and lower motor neurons. That has a huge affect on the way that the disease presents. The explanation that the muscles atrophy simply from disuse is misleading - it makes it sounds like using the muscle (action potential firing) is the primary thing that maintains muscle bulk. Nerves provide trophic factors to muscles that prevent atrophy.
Sarah Hajj (1 year ago)
Thank you for saying this! I am studying from this material and considered using his diagram, I'll adjust my diagram now, thanks again!
graciously grace (1 year ago)
I thought it was meant for medical students :/
Love the subtle UGA shout-out
Ashwin Ramaswamy (1 year ago)
3:51 Mispronounced 'criminal' there
mywavesofgrain (2 years ago)
Oh your kids loved that I bet! ! Thank you for everything you do at Khan Academy! Also in more recent years ALS Steve Gleason from the New Orleans Saints. http://www.nola.com/movies/index.ssf/2016/01/steve_gleason_documentary_pick.html
Prateek Shukla (4 years ago)
Nice video but i still dint u derstand the reason behind the ice bucket challenge. Can u put some light on that?
Matías Bruno (4 years ago)
Wow, the video tutorial about the ALS really makes a difference here, thanks.
Lee Jason (4 years ago)
Please Support me for my Education!  http://www.gofundme.com/dzi36g
alfredo gomez (4 years ago)
ares106 You must be crap yourself. 
alfredo gomez (4 years ago)
Its the mother of all diseases
Zach Alan (4 years ago)
I laughed hard when he said the other Salman Khan.
Matthew Lahman (4 years ago)
It's caused by acidic lymphatic accumulations that degenerate the nervous system. The cure is a raw food diet, aggressive juicing and sunshine in your eyes. The raw food and juicing dissolve and cleanse out the accumulations damaging the nerves and preventing the immune system from repairing and the photons entering the eyes directly powers the DNA regeneration process and recharges the CNS to amplify the nerve signals to overcome the impedance by the interstitial lymphatic residues. The residues are generated by meat, dairy and cooked grains.
Penina S. Finger (4 years ago)
We have an immediate family member suffering from this disease, and are grateful for this video. It adds to increased awareness and has raised a lot of money, which we appreciate. I don't have the exact numbers in front of me, but awareness of ALS through the ice bucket campaign has been significantly increased. Funds raised for research also dramatically exceeded expectations. Indirect benefits: other nonprofits are taking note. It's my hope that a cause that is as close to home for you will be inspired to create an upbeat and wildly successful campaign, and bring more issues closer to resolution.
Arisha Nazir (4 years ago)
This is great! I love how you nominated the 'other' Salman Khan love it!
saracasm.x (4 years ago)
Awe your kids are SO cute! I wish to see them do the ice bucket challenge :)
pr (4 years ago)
Steven Loomis, You should thank you god for being able to simply turn a faucet to get water whenever you want. As you run and waste that water just remember that there are millions who have limited access to this precious resource! And many day from polluted or contaminated water.
Mikko Finell (4 years ago)
Yeah Sal should have put that water in a package and posted it to to Africa instead am I right? That's what you are saying?
tayibveligeorge (4 years ago)
you r d best Sal!!!
PTD (4 years ago)
another salman Khan :))
Abhinav Khanna (4 years ago)
Dear Mr. Khan sir, I would like to point out a technical difference, although it is possible I may altogether be quite wrong, giving the fact that I am neither a doctor by profession, nor as knowledgeable as you are. There is a difference between Lou Gehrig's disease or also called as ALS and Motor Neuron Disease. There are various kinds of MND (4 I believe) out of which ALS is one of them. Stephen Hawking does not have ALS, he has MND (one of the remaining 3 kinds, which one it is not possible to tell without performing a spinal autopsy, which can only be done after his death, for the  obvious reasons). Him having MND, is one of the many reasons he has been able to live quite long. ALS, as you know has a lot lower life expectancy, with it decreasing as and when the diagnosis take places at a later age. About 4% of the people last more than 10 years, and almost no one has lasted as long as Mr. Hawking. He has MND, not ALS.
Foley0994 (9 months ago)
Motor neurone disease (MND) is the technically correct name. Within MND there are a number of different patterns of disease, ie the way that it affects their motor neurones. ALS is the most common type of MND, and there are three other types, primary lateral sclerosis, progressive muscular atrophy, and progressive bulbar palsy. Some patients may have overlapping/combined forms.
Abhinav Khanna (4 years ago)
Sorry to hear about your mom haing ALS Dianna!
dianna83301 (4 years ago)
ALS/MND = same thing. In Europe it is commonly called MND or Charcot disease, in the United States we call it ALS. It is broke down into catagories by how its first onset affects the body. My mother for example who died of ALS had  Bulbar it commonly affects the facial nerves making speaking difficult, however it affected areas throughout her body rather consistent making her entombed in her body unable to move anything except her eyes within the first year. She chose, as Steven Hawkings, to use a ventilator in which I cared for in my home. ALS is the sientific name for the disease, MND is not, and why it appears to cover a larger area like MD here.
don isiko (4 years ago)
+Abhinav Khanna If ALS is a kind of MND then... what's your point? Hawking had a different kinf of MND but that doesn't change the fact they fall under the same category :|
Abhinav Khanna (4 years ago)
+ItsOneInAMillion No Mr. One Million. MND's are types of diseases. ALS is one kind of MND. ALS not= MND. Yes ALS = Lou Gehrig's disease. There are different kinds of MND's of which ALS is one. And yes ultimately, it is where the mutation lies that will determine the life span of a sufferer. And yes, there are sub classifications/types of ALS which depend on length/location of mutation. Just like a particular type of cancer which has sub types. Every other MND again has sub-types. 
Andrew Johnston (4 years ago)
Great stuff!
DrStrangeLove2050 (4 years ago)
Ice Bucket Challenge  in  Khan-style!!
R Dahal (4 years ago)
Love how you've nominated Salman Khan. Thank you for the information on ALS, makes sense to know more about it than to just do the challenge. thumbs up
Arjun Nagarajan (4 years ago)
Other Salman Khan! LOOOOL!
Shiva Naidoo (4 years ago)
LOOOLL!!! The Other Salman Khan! Both are my dudes! :)
Anon Dee (4 years ago)
I always thought you where a white person, mrdarkvoicewhoexplainseverythingsowell
bidhut karki (4 years ago)
omg my two hero know each other.. Salman Khan know Salman Khan.. that is quite exciting..
Psquared (4 years ago)
Thank you, Sal! :-)
the9thGen (4 years ago)
the voices sound so different
Michael Duda (4 years ago)
Looking good, Mr Khan. But it bears pointing out that all the money raised won't go to research; they also provide patient care. I think that cuts to the national research budget and inadequate health care are the root problems that need a powerful lobby. 
Christopher Nguyen (4 years ago)
You know what? All other videos should be named like this one instead of ice bucket challenge. Generate the same awareness and also states what ALS stands for. 
Holic Shot (4 years ago)
Thank you for making this.
SpeedingSideway STi (4 years ago)
Question:  So if you say put yourself in a ice bath or put your head in ice bath for ( amount of time ). is it possible to induce a temporal ALS effect for a felt-able time??
koolioz (4 years ago)
Everyone should quit school and just watch your videos o.o
pr (4 years ago)
I only wish people have more appreciation for "water" and stop this nonsense. ALS is a genetic disease affecting primary European descents. If people just accept and let evolution through natural selection take its course and understand the balance it will achieve instead of this emotion based science they will do better. Eventually the surviving individuals will be healthier and more adapting. Awareness is always a good thing. In this case, it is overrated and unfortunately misguided. Always question EVERYTHING!
Vozdra Brate (2 months ago)
Lol, brutal comment! I think your absolutely right IF our current understanding of the world is true. But "Always question EVERYTHING!" :D
dianna83301 (4 years ago)
Good thing your still in school perhaps something will soak between those ears ... eventually. We can only hope. You should be made to do an entire thesis on ALS, 'Mr I know more than anyone,' you may find yourself with head buried deep in sand next to the Ostrich on the funny pages when you learn you know nothing of ALS  nor natural selection. 
The World (4 years ago)
Shutup
Leon Jarabek (4 years ago)
"it's natural selection." You know what else is natural selection? Almost everything people go to the hospital for. Pneumoniae and inflamated appendices were mostly fatal about 150years ago. deal with it.
Not a phony (4 years ago)
A lot happens later in life so people don't know when they have kids. That's not how evolution work. Perhaps you should watch the khan academy video on it?
mhtinla (4 years ago)
If Khan, Justin Bieber, and Britney Spears all did it, it must be a worthy fad. I heard Obama refused to do it !!!
Jessie Silbaugh (4 years ago)
If you could, Sal, please make another video discussing current therapy and experimental treatments. I would be extremely interested in learning about some of them. Fantastic video.
ybbolb (4 years ago)
http://www.alsa.org/about-us/financial-information.html Only 27% of funds received goes into research.
Joe Mc'Laughlin (4 years ago)
Ice bucket "receipt" challenge!!!!
TheTranMan23 (4 years ago)
hahaha, awesome Khan!
Zachary Arredondo (4 years ago)
Sal challenging the other Salman Khan just made my day.
THE16THPHANTOM (4 years ago)
i have seen your habitat...your home. you're a surprisingly regular guy, just with big brain, and more smarts.
Dr. B. Siroya (2 months ago)
dear Dr sb you are treating motor neurons disease 'll furnish your address to us so we may refer case to you
Saif S (4 years ago)
By nominating Salman Khan, the actor, he'll be spreading awareness to a whole region of the world (if he accepts the challenge, of course).
ares106 (4 years ago)
Your doing this crap too? Come on Khan I thought you where cool.
fromrussiawl1 (4 years ago)
+ares106 lol ur so silly. Must have grown up never exiting your comfort zone.
mhtinla (4 years ago)
+dianna83301 don't waste water 
dianna83301 (4 years ago)
+mhtinla the challenge was to dump a bucket of icewater on your head (to simulate the feeling of ALS) to catch that ahaaa moment from the freeze and to spread ALS awareness OR donate $100 dollars to your charity of choice. Obama chose to donate. If he did every charity whim or whatever, he couldn't very well do presidential duties and care for his own family. The fact he mentioned ALS was a win for the ALS community.
Bryce Crawford (4 years ago)
He went from cool to cold:P
ares106 (4 years ago)
+Abhinav Khanna your mother is an idiot XD
max (4 years ago)
This is awesome
James Jones (4 years ago)
Good job as always Sal
Alison Liu (4 years ago)
I love you sal and I love khan academy!!!
EpistemicPolymath (4 years ago)
Now that is how you spread awareness!
Dia Jasin (4 years ago)
This video should top the other videos cuz it raise awareness
Billygnr2003 (1 year ago)
Socky No
Socky Noob (4 years ago)
Agreed.
GENIUS316 (4 years ago)
"Today I consider myself the luckiest man on the face of the Earth" -Lou Gehrig a legend and a man affected by this horrible disease
Joe Mc'Laughlin (4 years ago)
Thunder?
Someone Super Cool (4 years ago)
Is that your version of the ice bucket challenge? lol :P

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