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Types of immune responses: Innate and adaptive, humoral vs. cell-mediated | NCLEX-RN | Khan Academy

3422 ratings | 1502199 views
Innate vs. adaptive immunity. Humoral adaptive immunity vs. cell-mediated adaptive immunity. Created by Sal Khan. Watch the next lesson: https://www.khanacademy.org/test-prep/nclex-rn/rn-immune-system/rn-the-immune-system/v/b-lymphocytes-b-cells?utm_source=YT&utm_medium=Desc&utm_campaign=Nclex-rn Missed the previous lesson? https://www.khanacademy.org/test-prep/nclex-rn/rn-immune-system/rn-the-immune-system/v/role-of-phagocytes-in-innate-or-nonspecific-immunity?utm_source=YT&utm_medium=Desc&utm_campaign=Nclex-rn NCLEX-RN on Khan Academy: A collection of questions from content covered on the NCLEX-RN. These questions are available under a Creative Commons Attribution-NonCommercial-ShareAlike 3.0 United States License (available at http://creativecommons.org/licenses/by-nc-sa/3.0/us/). About Khan Academy: Khan Academy is a nonprofit with a mission to provide a free, world-class education for anyone, anywhere. We believe learners of all ages should have unlimited access to free educational content they can master at their own pace. We use intelligent software, deep data analytics and intuitive user interfaces to help students and teachers around the world. Our resources cover preschool through early college education, including math, biology, chemistry, physics, economics, finance, history, grammar and more. We offer free personalized SAT test prep in partnership with the test developer, the College Board. Khan Academy has been translated into dozens of languages, and 100 million people use our platform worldwide every year. For more information, visit www.khanacademy.org, join us on Facebook or follow us on Twitter at @khanacademy. And remember, you can learn anything. For free. For everyone. Forever. #YouCanLearnAnything Subscribe to Khan Academy’s NCLEX-RN channel: https://www.youtube.com/channel/UCDx5cTeADCvKWgF9x_Qjz3g?sub_confirmation=1 Subscribe to Khan Academy: https://www.youtube.com/subscription_center?add_user=khanacademy
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Text Comments (234)
nadia c (1 month ago)
min 2:04 you mean only viruses have double stranded RNA not DNA
Aaron Roy Zender (1 month ago)
Can someone please give me a 15 sentence summary please?
Aaron Windham (3 months ago)
I'd rather an hour long video then having to spend an hour and a half waiting for videos to load, etc
Subtle Nature (3 months ago)
I knew this video would be interesting.
Jackie M (4 months ago)
This was actually more helpful than the 3 hours of lecture I sat through last week lol
Ali Alji (5 months ago)
His voice gives me PTSD of my highschool days *shivers*
Willow Jolie (7 months ago)
These things look "shady," I love the way this man explains biology.
Yuri Lee (7 months ago)
Only viruses have double stranded RNA.. no?
Julia Chang (8 months ago)
who's here for the AP Bio 2018 exam? T.T
Lujain AA (8 months ago)
I’m gonna kill my self if he doesn’t write the “s” that was erased from thymus by mistake💔
all.in.or.nothing _ (9 months ago)
Still thinking of my lymphos saying "Hey, you're just shady, imma eat you up"
Alwaleed Ibrahim (9 months ago)
I am in the 4th year of oral medicine school and still learning from these videos. Very helpful!
Suki Suuuki (10 months ago)
thank u
agizo duma (11 months ago)
khan academy so helpful, good work!
MrSurelysure (11 months ago)
i dont know but for me only viruses have double RNA?????????????????????????
Shaina Khan (11 months ago)
Nicole T (11 months ago)
Man you're the best
DarkAssassin (1 year ago)
i wish u cud do my exam for me
DarkAssassin (1 year ago)
very easy to understand didn't get it before thank u mate
Sharmila Patwari (1 year ago)
i want to create lectures of this type ( black screen and colourful brushes). how do i make them? which software should i use?
Summer Time! (1 year ago)
Dang it this is too simplified! I need to watch an hour long video lol
- UsernameTaken (11 months ago)
You can always make the vid speedup. It helps!.
Veronica Avalos (1 year ago)
You are so specific!! :)
Hamna Azhar (1 year ago)
As always, Thank u v.v.much sir! You made it all seem so easy
Dustin Smith (1 year ago)
That poor cell at the end looks like a sad potatoe.
Nicholas Costantini (1 year ago)
This video could be 4 minutes
kg062007 (1 year ago)
Watched this thinking it would help for the USMLE, but its too simple and he really didnt talk about anything
co co (1 year ago)
Thank you so much for creating Khan Academy. what a wonderful resource.
Marina (1 year ago)
I love you! I have no idea what I would do without your videos. You make the content so easy to follow and understand. Thank you so much for doing this!
Anju Soni (1 year ago)
i like your video it is a better explanition then my kadush teacher
Neta Burnum (1 year ago)
The measurement of immunogenicity is complex as it depends on many aspects. Appropriate assay strategy has to be selected specifically for each project.
Danya Danya (1 year ago)
Thea (2 years ago)
Btw u said in the video u want to further explained the cell-mediated immunity in another video. Where is it? I couldnt find it. or I did misheard?
Thea (2 years ago)
Love your lectures. Easily understood. Thanks!
Numberonehusband (2 years ago)
I hope in the future your video will be recorded better. I can barely hear you and that is because I have my laptop turned up all the way up, until then I guess I will look elsewhere for my studies.
Dat Tran (2 years ago)
i dont get it
Numberonehusband (2 years ago)
perhaps it could be my laptop, I just checked using my phone and it is pretty loud. Thanks, cause I really like his videos.
Ellen osbourne (2 years ago)
i can hear him very clearly
Dat Tran (2 years ago)
Fire Blade890 (2 years ago)
you are so smart. hopefully I will pass my course and by a ducati
Anagha Mandhare (1 year ago)
not if you spell buy as by
FadeSkywards (2 years ago)
soup 890 nice bike :p
Reinier Herings (2 years ago)
Antibodies (produced bij antigens) are aspecific and produced by the humoral response, aren't they? How does that work?
Matilda H (2 years ago)
You are making my like so good man, thank you for making year 12 human bio so much easier!
alya prawoto (2 years ago)
his handwriting is beautiful
SG amethyst (2 years ago)
"this thing looks shady, let me eat it up, let me kill it" your hilarious, your bae, and is it wrong if your voice turns me on ...
Meer Nahro (2 years ago)
+SG amethyst nah girl, i won't sue you
SG amethyst (2 years ago)
Yes I'm a girl. I love smart guys and his voice is sexy AF. Sue me 😂😂
RoFo 1020 (2 years ago)
+SG amethyst lmao yo this is khan academy n ur talkin bout ur turned on by dudes voice
Fire Blade890 (2 years ago)
+Meer Nahro both
Meer Nahro (2 years ago)
are you a girl? or gay?
L O (3 years ago)
his voice making me horny.. hmmm
Shahad Hamed (3 years ago)
i really wanna print this brain storming :(
Jamal Jabril (3 years ago)
way better than a 3 hour lecuture
Vanshaj Saini (3 years ago)
ummm... what is the program that you use?????
Jonika Weerasekare (3 years ago)
Don't you mean dsRNA when referring to virus genomes
Ashwin Bhardvaj (3 years ago)
+Jonika Weerasekare No viruses usually have single stranded rna as their genome. This kinda helps in a faster reverse transcription (y'know, synthesizing dna out of rna). So that they can multiply as fast as they can and make more copies.
Leonardo Gonzalez (3 years ago)
So can anyone explain why is it that the purpose of immunotherapy for allergies is to direct the immune response away from humoral immunity and towards cellular mediated immunity? if the difference between humoral and cellular is just whether the cell has been infected or not?
Josew Mumirah (3 years ago)
thank you
Ruth E. (4 years ago)
I have missed your voice! Weird? No!... it's been about 2 years lol. And you just helped me get an A in Biology. 
Anju Soni (1 year ago)
Ruth E. १o
L O (3 years ago)
+Ruth E. I know, hes voice making me horny... Love to mess around with him:)
hay-zbarz (3 years ago)
+Esther. Ruth he just helped you get an A? so how did you miss hes voice lol you came back to write this
Siti Ayra Akmad (4 years ago)
Mr. Khan, please never get tired of doing this stuffs. It really helps me a lot. :) Thanks. Godbless 😊
RG Kumar (4 years ago)
Has anyone realized that the immune system is a lot like clash of clans
James Phelps (4 years ago)
humoral, doesn't mean it's funny , hahaha
Elizabeth Burke (4 years ago)
Thanks for all our help with this difficult immunity chapter! I think I get it now! Yay! I will definitely be subscribing to these videos.
Sai Kumar (4 years ago)
long live khan academy...............
athenaatwar475 (4 years ago)
Only viruses have double stranded DNA, huh? Lol no @2:10
Nick (1 year ago)
lmao cells have dsRNA
Martin Ramirez (2 years ago)
Baltimore Classification of Viruses
topkhani (3 years ago)
He is not speaking at that level..in 30 mins how can he.. he is explaining basic immune response NOT virology.. But yeah, I just rechecked, he did say that only virus has dsDNA while mimicking a WBC thoughts. He is also right because DNA should be in Nucleus not in interstitial space or serum where WBC operate. Any that are found where WBC operate must be virii or some fragment that must be removed..
athenaatwar475 (3 years ago)
+topkhani nah he's still wrong. He said leukocytes respond non-specifically to double-stranded DNA, as if double-stranded DNA is somehow foreign and indicates a virus. Pretty sure he meant dsRNA. but DNA isn't always double stranded. there are single stranded DNA viruses.
topkhani (3 years ago)
+athenaatwar475 NOOOOO - he is right. DNA is always double stranded no matter where or what. Yes, there are RNA viruses - AIDS virus is an example. It produces a special enzyme called reverse transcriptase which actually can reproduce a DNA strand from that RNA strand. Then only it can replicate from that newly made DNA..
TheNinjaMonkey31 (4 years ago)
May sound stupid, but what application is this presentation done on? It would be helpful for me to help create revision posters etc. Thank you. Fantastic videos too!
Teme Leader (4 years ago)
Dear Khan Academy, I want say thank you very much for your outstanding work. I am so blessed to have this access and As being Medical student I always looked over more details.So i found a wonderful website (Khan Academy). I have one question, About MHC1. I know it interacts CD8. It is found in all nucleated cell, except RBC. My question is when we do blood transfusion, what about if we have an infected Rbc in specific. Can MHC1 respond and Can CD8 kill all the cell? sorry, I don't how much clear this question is, but i am kind of wondering....peace. 
tarun bhatia (2 years ago)
+temesgen sinamo sure
Zlatan Ibrahimovic (4 years ago)
TheDkclark10 (4 years ago)
I have been using these videos for supplementary learning because my college professor does NO sort of visual teaching. It's terrible for me! So after class I come and find the video that correlates with the lecture and I think it's the only reason I might pass my final tomorrow! Thanks.
musarch91 (4 years ago)
Vamsi Krishna Chowdary (4 years ago)
Khan [email protected] T-Lymphocyte is divided into "helper T cells, memory T-cells, suppressor T cells, and killer T cells.  (Not only T helper and Tc cells) you would have discussed about these too.  thank you
elvakrose abok (4 years ago)
"humoral.. doesn't mean it's funny" gets me every time
오유이 (1 year ago)
same. hahahahahaha
Asia Mae (3 years ago)
I thought I was the only one that laughed lol
Divya Adhikari˚͜˚ (4 years ago)
Thank you so much!!! it's a crystal clear lecture video :)
Wasim Patel (4 years ago)
I have an essay on " how does the immune system recognise and destroy virus-infected cells " . Should i use the cytotoxic pathway because the pathogen has infected a cell? Any suggestions ? Thanks
Alex Dutka (4 years ago)
someone goes to john moores!!!!
theethythou (4 years ago)
So I played the immunology playlist & the first thing they said is that there was a previous video of innate immunology. WTF?
sakina shaiwala (4 years ago)
Videos really helped me....
Tay Foedoerovna (4 years ago)
These videos are the reasons why I pass biology.
hano adn (5 years ago)
thanks soooo much
Jess R (5 years ago)
Thanks man your videos are awesome
Maria Tunno (5 years ago)
Very helpful, thank you! :)
fleshcookie (5 years ago)
These videos are a fantastic overview of the immune system. If you are taking an immunology course watching these will help you immensely throughout
I am Dtram (5 years ago)
@Ovi, yes obviously but he said, "only viruses have double stranded DNA" which is very much not unique to viruses. So he probably did mean dsRNA at that point in the video.
TooNu (5 years ago)
Sal you are a wonderful human being.
Keston Trammell (5 years ago)
Great Video.. although not specific, it helps me get the big picture
Bon H (5 years ago)
don't just watch it, read it in the book.
coldjeanz (5 years ago)
he takes too long to explain shit and doesn't even go into enough detail. overrated as fuck
POOJA GAIKWAD (5 years ago)
thnk u very much it helped me to undestand this topic a bit more better way.....
SH0TTY2Y0B0DY (5 years ago)
Watched this for the third time and still don't understand. I tried watching the innate vid first but you lost me
Patrick Ho (5 years ago)
Is this one person making all these khanacademy videos?
Bitha Elias-Jordan (5 years ago)
you're awesome
ladykapplez (5 years ago)
I am sure double stranded DNA is found in some viruses i.e. Hepatitis B, herpes virus family incl. Herpes simplex virus 1 & 2, varicella-zoster virus, cytomegalovirus, & Epstein-Barr virus, adenoviruses, papillomaviruses, polyomaviruses & poxviruses such as smallpox.
adela2014 (5 years ago)
both are specific
kittywaymo (5 years ago)
Awesome presentation
Meike Simms Media (5 years ago)
is humoral non-specific immune response and cell-mediated is specific response?
ksenia kz (5 years ago)
HSV, T7, T4, λ phages and many more
Bee Cee (5 years ago)
Fairly sure double stranded DNA isn't found in viruses
Anita Gabriela Pardo (5 years ago)
you are a G !!!!!!!!!!!!!!!!!!!!!!!!! my god !
Chiitownboy23 (5 years ago)
i love this man
Flowmar (5 years ago)
I'm convinced he has magical powers. Studying for Calculus and a Microbiology test taught by the same dude [who puts everything in (basically) lamens terms]?? Freaking amazing. Thank you so much, good sir. You have helped me and probably countless others pass their classes.
jordanka Nenkova (5 years ago)
Thanks God there are people like you!!!
spidaxtreme (5 years ago)
Instead, of heard of the aquired immune respone, and what you call apdapted, I call active immunity. Or mabey you did say it but i didnt hear it.
Cindi Martinez (5 years ago)
Thank you so much for taking your time to teach us in simpler terms. God bless you! You are helping a lot of students who are stuck trying to understand what we are studying. And you make it so much easier for us. So thank you thank you!
Cindi Martinez (5 years ago)
wow. i can't believe you teach this too. i was watching your organic chemistry videos. you genius, why can't you teach at school????!
Matthew E (5 years ago)
Did you mean double stranded RNA around 2:03?
ImortalPkin (5 years ago)
So basically, the humoral response is when the pathogen is in the extracellular space and the cell mediated response occurs when the pathogen gets into the intracellular space. Is this correct?
Sara F (5 years ago)
If it weren't for Khan Academy I would probably be failing AP Biology right now...
nscheibe1 (5 years ago)
Cytotoxic T cells are a part of cell-mediated immunity. See Peter Parham's "The Immune System", page 90.
rishabhw96 (5 years ago)
Hi Mr. Khan, I think you meant @2:05 "Double stranded RNA" instead of "Double stranded DNA."
Kishore Mishra (5 years ago)
best teacher i have ever seen !
Mike Fawcett (5 years ago)
What software does he use for this presentation?
69harbir (5 years ago)
quite a big mistake but yeah he did mean rna
memorycardslut (6 years ago)
only viruses have ds DNA???? you mean ds RNA right???

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